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BACKGROUND: COVID-19 pandemic situation made the pharmaceutical companies develop the vaccine with different formulations in a short period. OBJECTIVES: The main objective of the review is to focus on different types of vaccine formulations available globally and the importance of technology transfer in vaccine development associated with potential risks. RESULTS: Research on vaccine development led to various types of vaccines, such as Inactivated vaccines, live attenuated vaccines, Ribonucleic acid (RNA) and Deoxyribonucleic acid (DNA) vaccines, viral vector vaccines, and Protein Subunit Vaccines for COVID-19. But the process of vaccine development and technology transfer is lined with various risks and challenges. Through risk assessment, we found some major potential risks involved in product development; this leads to a smoother and more efficient method to develop safe vaccines available for public health. CONCLUSIONS: This review will explain the significance of technology collaboration for the faster development of various formulations of vaccines globally.

Oral administration is one of the most convenient forms for the intake of drug due to ease of administration, painless , versality and paramount patient compliance. The demand of fast disintegrating tablets has been growing, during the last decades especially for geriatric and pediatric patients due to dysphasia. So the new drug delivery known as orally disintegrating tablets came to existence. An attempt has been made to prepare fast dissolving tablets of Gabapentin using super disintegrants like cros carmellose sodium, crospovidone, PVP K-30. All the formulations were evaluated for post-compression parameters like hardness, friability, dug content uniformity, dissolution test and disintegration test. The  max of gabapentin was scanned for 0.1N HCL buffer. The maximum absorbance 221 nm was done. Finally F3 formulation is best formulation based on drug release characteristics

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