Bradykinin, as prepared by incubation of plasma globulins with the venom of Bothrop8 jararaca (Rocha e Silva, Beraldo & Rosenfeld, 1949), can be assayed upon the guinea-pig ileum, producing a typical contraction of the slow type, not influenced by atropine or anti-histamines. From the crude material, bradykinin is quantitatively extracted
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