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Introduction. Inadequate water is the second risk factor for the development of diseases after poverty. Therefore, one of the most important tasks in the sphere of creating the sanitary and epidemiological welfare of the population of the Russian Federation is to provide it with benign drinking water, safe in epidemiological terms and harmless in chemical composition. The purpose of this work. Conducting a hygienic assessment of the quality of drinking water for the content of this trace element at the regional level is very relevant as fluorine is important for human health, and the main way of its entry into the body is water. Material and methods. The paper presents data of own research for 2018. During this period, there were studied about 150 water samples of centralized water supply in the Vladimir region, most of which were selected in the largest settlements. The content of fluoride ions in water was determined by the method of capillary electrophoresis (HDPE F 14.1: 2: 4.157-99). As a result of the study, the Vladimir region was found to be characterized by a significant differentiation (from 0.05 mg/l to 2.75 mg/l) in the content of fluoride ions in the centralized supply water. A map was constructed for ranking the regions of the region for the content of fluoride ions in the centralized supply water. Discussions. In eight districts of the region, the fluorine content in water is much lower than the optimal values; in five regions, an exceeding the maximum permissible concentrations was detected; and only in three regions the average values are close to optimal. The different content of fluorine in water in the districts of the region is due to the natural factor of the given geographic zone. Conclusion. Providing the population of the region with benign drinking water requires a set of various measures with the development and implementation of programs to improve the water supply of populated areas. At the forefront is the individual prevention of tooth decay and fluorosis, in which an important role is played by health education, advertising of preventive drugs that have been praised by specialists.

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