Physicians are motivated to use e-health technology. Use of modern technology enables knowledge extraction which can be used to improve diagnostics and treatment. At present Electronic Patient Record (EPR) are also shared through cloud among hospitals. Protection of EPR is important to protect the ownership particularly when the data is shared with third parties. Digital watermarking is a proven technique to achieve this goal. Digital watermarking technique can be employed for data hiding and to ensure integrity and authenticity of medical image. Considering this broad scope, a fresh and reversible watermarking scheme is recommended to report this safety production. Hospital Logo, Hash of ROI, Doctor Identification Code (DIC) is embedded using Recursive Dither Modulation (RDM) algorithm subsequent to wavelet transform and singular value decomposition. To improve the performance of the scheme differential evolution based optimization technique is proposed. The scheme is reversible and can also perform tamper detection.