In a prospective, nationwide, decentralized breast cancer project conducted by The Danish Breast Cancer Cooperative Group (DBCG) the recurrence rate within the first year after surgery was analysed in relation to tumor anaplasia. One thousand forty-eight patients met the requirements of eligibility, i.e. tumor size less than or equal to 5 cm with negative axillary nodes, and no skin or deep invasion. The recurrence rates in tumors with anaplasia Grades I, II, and III were 4, 9, and 14%, respectively (p = 0.001). Therefore, it seems possible, prospectively, among otherwise prognostically favorable patients, to select a group with high risk of recurrence which might benefit from adjuvant systemic therapy.

ABSTRACT. 281 patients who had permanent pacemaker implanted between 1961‐73 have been checked at 4 month intervals over a period of 1 to 13 years. Complications from the pacemaker pocket comprises haematoma, skin necrosis, infection of the pocket, allergic reaction to the pulse generator, pacemaker twiddlers syndrome, and muscle contractions. The causes for and treatment of 11 cases with haematoma, skin necrosis or infection are dealt with in detail.

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