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Synovial mast cells produce proinflammmatory cytokines and may thus contribute to the inflammation in RA.

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The economic costs of ankle fractures treated operatively with self-reinforced polyglycolide acid (SR-PGA) screws, with self-reinforced poly-L-lactide acid (SR-PLLA) screws or with metallic implants was determined. All patients were divided into three groups according to the fixation material used. Open and otherwise complicated fractures were excluded. The total expense of operations in each group was taken into account. The average total cost of an ankle fracture fixed with SR-PGA screws was Pounds 3503. In the SR-PLLA group it was Pounds 3906, and in the metallic group it was Pounds 4514. Total expenses were Pounds 1011 higher in the metallic group than in the SR-PGA group, and consequently, expenses in the metallic group were Pounds 608 higher than in the SR-PLLA group. According to this study, it seems that absorbable fixation devices are more economical than metallic implants in operative treatment of ankle fractures though as part of the differences in total expense in this series is due to the age of the patients and other dissimilarities between these groups, the results have to be interpreted carefully.

The outcome of olecranon and patella fractures fixed with biodegradable implants (self-reinforced poly-L-lactide wire combined with self-reinforced polyglycolide screw or self-reinforced poly-L-lactide plug) or with metallic implants (tension band wiring, Kirschner wire and metallic cerclage wire) was compared in a prospective, randomized study. Twenty-five olecranon fractures (15 with biodegradable implants and 10 with metallic ones) and 10 patella fractures (6 with biodegradable implants and 4 with metallic ones) were treated. There were no differences between these methods in outcome. Olecranon and patella fractures can be treated using biodegradable implants successfully. The total expenses are lower because a second operation is not needed to remove the implants after fracture consolidation.