Naringin is a dietary flavonoid abundantly produced as secondary metabolite by various citrus fruits including Citrus paradise, Citrus nobilis, Artemisia selengensis, Citrus junos, Citrus sinensis, Citrus unshiu, Citrus tachibana, Artemisia stolonifera, roots of Cudrania cochinchinensis, aerial parts of Thymusherba barona, fruits of Pon cirus and other citrus species. 20 Naringin has been reported to act as an antiviral, anticancer, hepatoprotective, cardioprotective and neuroprotective agent in several preclinical studies. 21-25 It has been found to possess free radicals scavenging, metal chelating and antioxidant properties. 26-34 Naringin has been reported to protect against the radiation and doxorubicin-induced chromosome damage earlier. 30,35,36 It has been found to protect against doxorubicin-induced cardiotoxicity in vitro and in vivo. 37 Naringin has been reported to reduce incidence of benzo-a-pyrene-induced forestomach carcinoma in mice. 38 It has also been found to protect against the iron-induced toxicity in vitro and in vivo. 31,38 Naringin acts as an antidiabetic, antifibortic, anti-inflammatory, antidyslipidemic antiosteoporotic agent and protected against lipodystrophy and cognitive damages. 39-42 It has been reported to be cytotoxic against breast cancer and HeLa cells and effective in the treatment of Walker's carcinoma in rats. 43-45 Naringin has been reported to protect against the doxorubicin-induced cardiotoxicity without compromising with its antitumor activity in mice. 24 The effect of naringin on the doxorubicin-induced lung toxicity has been not studied, therefore, the present study was undertaken to obtain an insight into the effect of naringin against doxorubicininduced oxidative damage in the lungs of albino rats.