Within the Middle East region the development of large gas accumulation has resulted in a need for hydrate control within the produced fluids during the winter months. Development of kinetic hydrate inhibitors (KHI) as an alternative to thermodynamic hydrate inhibitors (THI) such as methanol or mono ethylene glycol (MEG) has resulted in a significant reduction in process equipment size and associated operational costs but the disposal of the resulting KHI that predominately partions into the produced water and corrosion inhibitor constantly added to production lines has raised concerns about formation damage within the injection/disposal wells under matrix flow conditions This paper will present details from a set of corefloods which look at produced water re injection (PWRI) under matrix flow conditions within carbonate cores and the observed damage such KHI and KHI/CI solutions can produce within Arab D formation rock. The coreflood tests generated pressure profiles, cation, pH and KHI concentration within the coreflood effluent during the injection of these fluids to fully understand the process occurring within the rock (dissolution, ion exchange, precipitation/adsorption, filtration). The study then looked at mitigation methods for the damage that could be potentially induced and then based on understanding the two generations of KHI and associated corrosion inhibitor molecule structure what changes could be made to the produced fluid composition to eliminate the damage from forming in the first place. The paper outlines the mechanism of damage and mitigation to a flow assurance challenge that is receiving a significant amount of focus within the Middle East region at this time.