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The paper examines the cross-impact of state programs' implementation. The research methodology rests upon the theory of public management efficiency, the concept of New Public Management and the system-based approach to its analysis. In the course of the study, the authors apply the regulatory, comparative and context methods and the verbal modelling. The researchers review a number of scientific works and reference documents, as well as perform a content analysis of the regulatory framework in the subject area under consideration. The article substantiates the relevance and the need for investigating cross-program effects and identifies the prerequisites for the improvement of state programs' effectiveness evaluation. The study clarifies the meaning of the term "crossprogram effect" and discusses how it differs from a multiplier effect. The research presents a classification of cross-program effects and develops the methodological guidelines and the conceptual diagram for assessing the cross-impact when implementing state programs in a constituent territory of the federation. The authors propose the indices such as the cross-impact of a state program and the cross-effectiveness of a state program and outline the difficulties and limitations of the given approach to the assessment of cross-program effects. The results the evaluation are expected to optimize and improve the mechanisms of the program budgeting and strategic planning.