Manjishtha is one of the most clinically practiced herbs in Ayurveda System of Medicine. It is also immensely documented in Ayurvedic traditional literature for various diseases. Out of its entire therapeutic spectrum, herb is famous for its activity on various skin diseases/blood disorders. The Latin name of Manjishtha is Rubia cordifolia Linn (Family: Rubiaceae) and is commonly sold under the trade name 'Majith' in Indian Market. In recent period many experiments were carried out in different field like Pharmacognosy, Pharmacology, Chemistry, etc to trace out valuable components from this plant. Being one of the major herbs in Ayurveda, it has attracted many researchers to explore its potential in Pharmacological field. It is observed that most of the screened Pharmacological results were seemed to be already documented in Ayurveda directly or indirectly since centuries. This documentation is mostly in the form of Sanskrit Sutra and carries large concealed information for those who understand the conceptual depth of Ayurveda. Here is a review of screened information verses Ayurvedic literature which is validating the claims made by the ancient sages.