A follow-up study including examinations made by a paediatrician, an ophthalmologist and a psychologist and complemented with EEG-recordings and a number of laboratory determinations was performed at the age of 3 years on 41 children who had received phototherapy during the first week of life and on 42 control children of the same age. No differences were found in growth, development, social maturity, neurological or ophthalmologic disorders, EEG-recordings or laboratory determinations between both groups. It seems unlikely that phototherapy causes any harmful longterm effects provided that the eyes are shielded.

Summary Three cases of cebocephaly with no extracranial anomalies are reported. In two cases chromosomes were examined. The karyotype was found normal in both cases. No abnormal aminoacids in cerebrospinal fluid were detected.

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