A new catalytic system containing ferric chloride, activated carbon, and hydrazine has been proposed for the reductive cyclization of -dialkylamino-2-nitrostyrenes to give the corresponding indoles (Leimgruber-Batcho synthesis). Various substituted indoles may be obtained in high yield under these conditions.
An unusual catalytic system containing ferric chloride, activated carbon, and hydrazine is successfully applied for the reductive cyclization step in the Leimgruber—Batcho indole synthesis.
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