BackgroundNeuropathic pain caused by the musculoskeletal diseases has recently been the focus of numerous studies.ObjectivesThe aim of this study was to estimate the structure of pain syndrome and reveal the presence of neuropathic pain component in patients suffering from the musculoskeletal diseases.MethodsWe've examined 68 patients aged 45-85 years (average age 67,6±1,3years). Patients were divided into 3 groups: A – patients with osteoporosis and vertebral fractures (N=29), B – patients with low back pain (N=22), C – patients with osteoarthritis of knee joints (N=17). To assess the NP component we used painDETECT, LANSS, DN4 questionnaires.ResultsRegression analysis shows correlation between the questionnaires: LANSS and painDETECT (r=0.73, p=0.000001), DN4 and painDETECT (r=0.73, p=0.000001). 63,6% of patients with osteoporosis examined by painDETECT were unlikely to have the NP component, 17,2% might possibly, 17,2% – probably. LANSS scale: 24,1% were probably to have NP. DN4 scale: 37,9% probably had NP. 63,7% of patients with low back pain examined by painDETECT were unlikely to have NP, 22,7% might possibly, 13,6% – probably. LANSS scale: 22,7% were probably to have NP. DN4 scale: 36,4% had probably NP. 64,7% of patients with osteoarthritis of knee joints examined by painDETECT were unlikely to have the NP component, 29,4% might possibly, 5,9% - probably. LANSS scale: 23,5% probably had NP. DN4 scale: 41,2% had probably NP.ConclusionsThus, in patients with musculoskeletal diseases the pain syndrome may include NP features. Identification of these would promote a treatment strategy targeted at the NP.Disclosure of InterestNone declared