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Cardiovascular disease is the cluster of syndromes of blood vessels and heart that consist of hypertension, coronary heart disease, rheumatic heart disease, congenital heart disease, Cardiomyopathies, cerebrovascular disease, peripheral vascular disease and heart failure. Strawberry (Fragaria x ananassa) is produced in marketable scale because of the use of chemicals to retain the quality of fruit during storage and transport is prohibited, high perishability and short postharvest life. In, adults, the leading cause of cardiovascular disease is hypertension. It affects approximately 18% in Pakistan. As increase in blood pressure increases the threat for cardiovascular disease mortality. ACE inhibition is an important target for hypertension management. It was observed that the purified ellagitannins had higher ACE inhibitory activity than ellagic acid and strawberries (Lee, 2006).

Black cumin is deliberated as herbal medicine for a number of diseases in Unani traditional medicine. Except death and aging, black cumin has been named as a cure for all diseases by a Hadith of the Holy Prophet Muhammad P.B.U.H in Islamic medicine. Not only in Islam but in the Bible and other religious sources the black cumin has been recommended of therapeutic use well. Black cumin has been traditionally used in the treatment of several diseases as a herbal medicine such as infertility, fever, chronic headache, migraine, dizziness, chest congestion, paralysis, dysmenorrhea, cough, bronchitis, asthma, obesity, diabetes, infection and inflammation, rheumatism, hemiplegia, back pain hypertension and gastrointestinal disorders such as dyspepsia, flatulence, diarrhea and dysentery. In accumulation, black cumin oil has been used as a balm for aid from nasal ulcers, orchitis, eczema, abscesses and swollen joints. Black cumin has also been conventionally used to treat respiratory disorders such as bronchospasm, asthma and chest congestion in combination with honey.