This report describes surgical observation and histopathological findings in a case of a 44-year-old male with leiomyoma of the iris in his left eye which had initiated from uveitis. In view of clinical efficiency and electron microscopic detection of leiomyoma, it is recommended that the tumour be excised after freezing coagulation. For confirmative diagnosis of leiomyoma of the iris, an electron microscopic detection is necessary to demonstrate the characteristic findings including cells with cigar-shaped nuclei, cytoplasmic and plasmalemma1 density, fine filaments, surface-connected vesicles and basement membrane.

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