The Double Chooz Experiment presents an indication of reactor electron antineutrino disappearance consistent with neutrino oscillations. An observed-to-predicted ratio of events of 0.944 ± 0.016 (stat) ± 0.040 (syst) was obtained in 101 days of running at the Chooz Nuclear Power Plant in France, with two 4.25 GW th reactors. The results were obtained from a single 10 m 3 fiducial volume detector located 1050 m from the two reactor cores. The reactor antineutrino flux prediction used the Bugey4 flux measurement after correction for differences in core composition. The deficit can be interpreted as an indication of a non-zero value of the still unmeasured neutrino mixing parameter sin 2 2θ13. Analyzing both the rate of the prompt positrons and their energy spectrum we find sin 2 2θ13= 0.086 ± 0.041 (stat) ±0.030 (syst), or, at 90% CL, 0.017 < sin 2 2θ13 < 0.16. We report first results of a search for a non-zero neutrino oscillation [1] mixing angle, θ 13 , based on reactor antineutrino disappearance. This is the last of the three neutrino oscillation mixing angles [2,3] for which only upper limits [4,5] are available. The size of θ 13 sets the required sensitivity of long-baseline oscillation experiments attempting to measure CP violation in the neutrino sector or the mass hierarchy.In reactor experiments [6,7] addressing the disappearance ofν e , θ 13 determines the survival probability of electron antineutrinos at the "atmospheric" squaredmass difference, ∆m 2 atm . This probability is given by:where L is the distance from reactor to detector in meters and E the energy of the antineutrino in MeV. The full formula can be found in Ref.[1]. Eq. 1 provides a direct way to measure θ 13 since the only additional input is the well measured value of |∆m 2 atm | = (2.32Other running reactor experiments [9,10] are using the same technique.Electron antineutrinos of < 9 MeV are produced by reactors and detected through inverse beta decay (IBD): ν e + p → e + + n. Detectors based on hydrocarbon liquid scintillators provide the free proton targets. The IBD signature is a coincidence of a prompt positron signal followed by a delayed neutron capture. We present here our first results with a detector located ∼ 1050 m from the two 4.25 GW th thermal power reactors of the Chooz Nuclear Power Plant and under a 300 MWE rock overburden. The analysis is based on 101 days of data including 16 days with one reactor off and one day with both reactors off.The antineutrino flux of each reactor depends on its thermal power and, for the four main fissioning isotopes, 235 U, 239 Pu, 238 U, 241 Pu, their fraction of the total fuel content, their energy released per fission, and their fission and capture cross-sections. The fission rates and associated errors were evaluated using two predictive and complementary reactor simulation codes: MURE [17,18] and DRAGON [19]. This allowed a study of the sensitivity to the important reactor parameters (e.g.. thermal power, boron concentration, temperatures and densities). The quality of these simulations...

The simulation software for the ATLAS Experiment at the Large Hadron Collider is being used for largescale production of events on the LHC Computing Grid. This simulation requires many components, from the generators that simulate particle collisions, through packages simulating the response of the various detectors and triggers. All of these components come together under the AT-LAS simulation infrastructure. In this paper, that infrastructure is discussed, including that supporting the detector description, interfacing the event generation, and combining the GEANT4 simulation of the response of the individual detectors. Also described are the tools allowing the software validation, performance testing, and the validation of the simulated output against known physics processes.

The Double Chooz experiment has observed 8,249 candidate electron antineutrino events in 227.93 live days with 33.71 GW-ton-years (reactor power × detector mass × livetime) exposure using a 10.3 m 3 fiducial volume detector located at 1050 m from the reactor cores of the Chooz nuclear power plant in France. The expectation in case of θ13= 0 is 8,937 events. The deficit is interpreted as evidence of electron antineutrino disappearance. From a rate plus spectral shape analysis we find sin 2 2θ13 = 0.109 ± 0.030(stat) ± 0.025(syst). The data exclude the no-oscillation hypothesis at 99.8% CL (2.9σ).

Background and Purpose-Some previous Japanese cohort studies failed to show an association between smoking and stroke risk. Because such an association has been noted in other populations, this issue should be re-examined in a recent representative Japanese cohort with a higher total cholesterol level. Methods-A total of 9638 men and women aged 30 years and older without a history of cardiovascular disease (CVD) at baseline in 1980 were followed-up for 14 years. Results-We observed 203 stroke deaths (107 cerebral infarctions, 45 cerebral hemorrhages, and 51 others), 191 heart disease deaths, and 413 CVD deaths. The average serum total cholesterol level was Ϸ4.91 mmol/L. Cox proportional hazard ratios were calculated adjusting for age, systolic blood pressure, and other conventional risk factors. The hazard ratios for men who smoked 1 to 20 cigarettes/day for all strokes, cerebral infarction, and cerebral hemorrhage were 1.60 (95% CI, 0.91 to 2.79), 2.97 (CI, 1.27 to 6.98), and 0.42 (CI, 0.16 to 1.09), respectively, and for those who smoked Ն21 cigarettes/day, they were 2.17 (CI, 1.09 to 4.30), 3.26 (CI, 1.11 to 9.56), and 0.68 (CI, 0.20 to 2.33), respectively. For women who smoked Ն21 cigarettes/day, the hazard ratio for all strokes was 3.91 (CI, 1.18 to 12.90). For CVD, all heart disease, and ischemic heart disease, the hazard risks of smoking were significant (1.49 to 4.25) for men but not significant for women. Conclusions-Smoking in a cohort with moderate serum total cholesterol level was a potent risk factor for stroke, especially cerebral infarction, for both men and women, and for CVD and ischemic heart disease for men.