Keywords: Alkynes / C-C coupling / Copper / Nanoparticles / Titanium / Heterogeneous catalysis Copper nanoparticles on titania effectively catalyse the oxidative homocoupling of terminal alkynes in the presence of piperidine as a base in tetrahydrofuran (THF) or under solvent-free conditions. A wide range of diynes have been synthesised in high yields using low catalyst loading (1 mol-%

Homocoupling of Terminal Alkynes Catalyzed by Ultrafine Copper Nanoparticles on Titania. -A wide range of aromatic or aliphatic diynes are prepared in the presence of only 1 mol% Cu nanoparticles on TiO2. In many cases, higher yields are obtained at considerably shorter reaction times in the absence of a solvent compared to the reactions performed in THF. -(ALONSO*, F.; MELKONIAN, T.; MOGLIE, Y.; YUS, M.; Eur.