No abstract

Aminodeoxycelluloses were prepared by treating cellulose p-toluenesulfonates, which were prepared from various kinds of cellulose samples under various conditions, with a solution of ammonia in ethanol at 100° in an autoclave. From cellulose p-toluenesulfonates made at 0•‹, from never-dried, solvent-replaced regenerated cellulose, aminodeoxycellulose with a high degree of substitution (up to 0.82) was obtained with minimum side reaction. Acetylation and 2,4-dinitrophenylation of aminodeoxycellulose were studied. Some properties of aminodeoxycellulose are also reported.

From the reaction results of p-benzoquinone derivatives with various amino compounds, it becomes clear that chloranil reacts with ethylenediamine to afford an unexpected product. The spectroscopic analyses of the product show that this is an addition compound with some contribution of charge-transfer structures. Bromanil gives a similar product upon reaction with ethylenediamine.

SynopsisWe have prepared polyesters from succinyl chloride, adipoyl chloride, and telephthaloyl chloride with dibenzyl L-tartrate, polyurethanes from hexamethylene diisocyanate, toluene 2,4-diisocyanate, and methylene-bis(4-phenyl isocyanate) with dibenzyl L-tartrate. The molecular weights of these polymers were generally low except for one of the polyurethanes. These polymers were reduced to give those having carboxyl side groups. Potency for inducing interferon was tested for one of the polymers. The result was not encouraging in showing low activity.

Synopsis The anticoagulant activity of sodium aminopolysaccharide sulfates was tested in vitro by Lee and White method. All of them showed an activity in delaying coagulation of blood. Several sodium aminodeoxycellulose sulfates had higher anticoagulant activity than all of the commercial anticoagulants except for sodium heparinate. Some films prepared by treating sodium aminodeoxycellulose sulfates with formalin or polyvinyl alcohol also had an anticoagulant activity.