Background: Aim: To estimate microalbuminuria in non-diabetic patients with Acute Coronary Syndrome And assess the relationship between the two. Methodology: All patients age >18yrs, both sexes diagnosed as acute coronary syndrome based on history and relevant investigations and admitted in BLDEU'S Shri B.M PATIL Medical college hospital and research centre Vijayapur. microalbuminuria was measured at admission and compared with standard normal mean value. Results: This study was conducted on 60 patients, of the study group 70.0% were male and30.0% were female. The age ranged from 30 to 85 years of age. The mean age of thegroup was 55.5 ±13.19 SD. The known risk factors of ACS were studied and correlated,37.2 % of all patients were smokers, 31% were tobacco chewers, 24.7 % had diabetesmellitus, 31.8% were hypertensive and 8 % had family history of ACS. The meanmicroalbuminuria value in mg/dl for STEMI was 35 ± 0.30 SD, for NSTEMI it was 21±1.6 and for unstable angina it was 22 ± 1.0 SD. The mean microalbuminuria in patientswith ACS was 44.6 ± 3.2 SD mg/dl incompared to microalbuminuria levels of 30mg/l innormal population (p<0.0001). Conclusion: This study showed an correlation of microalbuminuria with ACS. This reinforcesthe fact that microalbuminuria acts as emerging potential risk factor marker.

BACKGROUND: Alcoholism is a signicant threat to public health in developed and developing countries. Over the last 30-40 years, alcohol consumption has increased in quantity and frequency. Alcohol use predisposes subjects to changes in lipid prole associated with coronary risk. AIM: 1] To study lipid prole in chronic alcoholics by measuring serum total cholesterol triglycerides, HDL, LDLand VLDL. 2]To compare lipid prole changes in chronic alcoholics and non-alcoholics MATERIALS AND METHODS: A Hospital-based cross-sectional study was conducted with patients attending the General Medicine department in Santhiram medical college and general hospital, of which 30 alcoholic and 30 non-alcoholic were taken into the present study. RESULTS: There was a signicant rise in TC, TGL, HDL, LDL and VLDL of chronic alcoholics compared with non-alcoholics with p-value 0.001, <0.001, 0.004, 0.290, <0.001, respectively. Lipid prole was compared among moderate and heavy drinkers and found increased levels of TC, TGL, LDL& VLDL with p-value <0.001, 0.001, 0.002 & 0.001 respectively in heavy drinkers. There is a decrease in HDLcholesterol among heavy drinkers compared with moderate drinkers, p-value 0.011, which is signicant. But remains elevated compared to non-alcoholics. CONCLUSION: This study shows that alcohol intake increases lipid parameters. Moderate alcohol intake increases HDL cholesterol, whereas heavy alcohol consumption increases TC, TGL, LDL& VLDLand decreases HDL.

BACKGROUND: To identify the impaired organ dysfunction and study the relevance of SIRS in predicting the organ dysfunction among 100 patients who fullled the criteria for SIRS AIM:1. To identify the organ dysfunction among patients with systemic inammatory response syndrome (SIRS). 2. To study the relevance of systemic inammatory response syndrome predicting an impaired organ function. MATERIALS AND METHODS: A six-month hospital-based prospective study was conducted in General Medicine, Santhiram Medical College, and General Hospital after approval from the Hospital Ethics and Research Committee. The study population consisted of patients admitted to this hospital who met the inclusion criteria. The clinical and laboratory proles of fty of these patients were examined. RESULTS: 35% of the patients belonged to the 36-55 age group, and 33% belonged to the 56-75 age group. The respiratory system was the most common site for the focus of infection leading to systemic inammatory response syndrome (SIRS). (40%). Our study's most common organ dysfunction was the renal system (39%), followed by the respiratory system (32%). Single organ dysfunction was commonly observed (36.4%), followed by 2 & 3 organ dysfunctions in 21.8%. 4 and 5 organ dysfunctions were observed in 10.9% and 9.1% of patients, respectively. The average number of days of hospital stay of the patients was 6-10 days, and the mortality was 21% in our study. The increase in the age of patients was associated with higher mortality in our study. Patients with SIRS criteria 2 had minimal organ dysfunction, whereas SIRS criteria 4 had the maximum number of organ dysfunctions. CONCLUSION:Thosepatientswithanincrease inSIRScriteriahadhigherimpairedorganfunctions andhighermortality.Hence thedocumentationof SIRScriteriainacutelyillpatientsisofparamountimportanceasithelpspredicttheorgandysfunctionsandtheoutcomeofthepatients.