No abstract

Abstract. To understand how cytokinesis is regulated during mitosis, we tested cyclin-p34 ~2 for myosin-II kinase activity, and investigated the mitotic-specific phosphorylation of myosin-II in lysates of Xenopus eggs. Purified cyclin-p34 ,~-~ phosphorylated the regulatory light chain of cytoplasmic and smooth muscle myosin-I/in vitro on serine-1 or serine-2 and threonine-9, sites known to inhibit the actin-activated myosin ATPase activity of smooth muscle and nonmuscle myosin (Nishikawa, M., J. R. Sellers, R. S. Adelstein, and H. Hidaka. 1984.

No abstract

No abstract