Background and Objectives:
There is as yet no suitable routine laboratory test for a blood transfusion service to detect bacterial contamination in platelets. This study evaluates the effectiveness and the applicability of short‐term bacterial culture for such a purpose. Materials and Methods: Samples from 5‐unit platelet pools were inoculated into an aerobic culture bottle, then monitored for 48 h at 35°C in an automated monitoring and detection system. Results: 26,210 whole‐blood‐derived platelet components were tested, of which 14 (0.053%) platelet units were found to be contaminated. In addition, nine of the associated red cell units and 4 fresh‐frozen plasma units grew the same organisms on culture. Conclusion: Short‐duration bacterial culture by an automated system is effective and suitable for routine screening in a regional transfusion center.
Background and Objectives: There is as yet no suitable routine laboratory test for a blood transfusion service to detect bacterial contamination in platelets. This study evaluates the effectiveness and the applicability of short–term bacterial culture for such a purpose. Materials and Methods: Samples from 5–unit platelet pools were inoculated into an aerobic culture bottle, then monitored for 48 h at 35°C in an automated monitoring and detection system. Results: 26,210 whole–blood–derived platelet components were tested, of which 14 (0.053%) platelet units were found to be contaminated. In addition, nine of the associated red cell units and 4 fresh–frozen plasma units grew the same organisms on culture. Conclusion: Short–duration bacterial culture by an automated system is effective and suitable for routine screening in a regional transfusion center.
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.