The devastating novel coronavirus (COVID-19) pandemic worldwide has become a global health crisis. This disease is highly contagious and caused by the transmission of severe acute respiratory syndrome, coronavirus 2 (SARS-CoV-2). To prevent the transmission of SARS-CoV-2, disinfectants and sanitizers are very effective and readily available preventive agents. In this study, knowledge, attitude and practice (KAP) levels of Bangladeshi people's were assessed regarding the use of disinfectants and sanitizers during the pandemic. An online questionnaire-based survey was conducted among the respondents from July 2021 to December 2021. A total number of 428 respondents participated in this survey. Data were analysed by the Statistical Package for the Social Sciences (SPSS) V26 software and interpreted. Results revealed that most of the respondents were knowledgeable, had a positive attitude and engaged in beneficial practice. Among the respondents, a significantly higher knowledge and practice score were observed among females (54.1% and 54.4%, respectively) than their counterpart. Moreover, people living in urban areas (71.7%) had a better attitude than the rural people (28.3%). In addition, a medium positive correlation between knowledge and attitude (r = + 0.482), a weak positive association between attitude and practice (r = +0.199), and a weak positive association between knowledge and practice (r = + 0.282) were found. Overall, majority of the respondents had better KAP scores in knowledge and attitude with relatively low scores in practice which indicates some space for betterment. Dhaka Univ. J. Pharm. Sci. 21(2): 117-126, 2022 (December)

The present study was carried out to assess and compare the analgesic and antioxidant potential of Citrullus lanatus rind and flesh extract. The methanolic extract of the rind and ethyl acetate extract of the flesh were evaluated for their in vivo analgesic activity through the acetic acid-induced writhing method on Swiss Albino mice. The free radical scavenging activity of the extracts was measured by total phenolic content measurement and the DPPH method. The flesh extract showed higher antioxidant activity than the rind extract in both methods. In case of the evaluation of analgesic activity, the results were obtained in a dose dependent manner. At 200 and 400 mg/kg doses, both extracts displayed moderate analgesic property in a statistically significant manner (p < 0.05) with respect to aceclofenac sodium. The flesh extract was found to provide a better effect than the rind extract in this case as well. It may be concluded that the ethyl acetate extract of C. lanatus flesh and the methanolic extract of the rind possessed potential antioxidant and analgesic activities and might be used as sources of nutraceuticals or functional foods. Bangladesh Pharmaceutical Journal 25(1): 67-72, 2022 (January)