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Iron oxides are naturally occurring compounds, and several methods have been developed for generating iron oxide nanoparticles (IONPs) with a focus on precisely modulating their size and physicochemical properties. Facile synthesis approaches, narrow size distribution, ease of surface modification, tunable magnetic properties, and size-dependent elimination from blood circulation, make IONPs attractive for use in different biomedical applications. This review describes the use of IONPs for application in tissue repair and regeneration with a focus on neural and musculoskeletal tissues.

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