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Background: Squamous cell carcinoma (SCC) of the dorsum of the tongue frequently presents as an exophytic mass mimicking benign lesions.Case Presentation: We report a case of a 69-year-old woman with an exophytic lesion on the dorsum of the tongue. She underwent biopsy twice prior to surgical excision. The biopsy specimens revealed epithelial hyperplasia, and the pathological diagnosis from the surgical material was well-differentiated SCC. Immunohistochemical findings of cytokeratin 13 (CK13), CK17, Ki-67, and p53 showed the pre-neoplastic nature of the hyperplastic epithelia in the biopsy specimens. Conclusion:Immunohistochemical staining is useful for the diagnosis of exophytic lesions of the dorsum of the tongue.

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Background Peripheral ameloblastoma is an extraosseous variant of ameloblastoma. We report a rare case arising in an extragingival location. Case Presentation The patient was a 79‐year‐old man with a firm nodule in the right‐side buccal mucosa. Imaging examinations showed a well‐demarcated mass in the right masticator space (infratemporal fossa). The diagnosis of ameloblastoma was made from the biopsy specimen. After conservative tumor excision, the patient had no recurrence during the follow‐up period of eight and a half years. The Ki‐67 labeling index indicated the nonaggressive nature of the tumor. Conclusion Conservative surgery is applicable to extragingival peripheral ameloblastomas.