Special digging machines are used currently in many countries when laying underground utility systems of various types. They are designed to form holes with a complex path. Vermeer, Straight Line, Ditch Witch (USA), Tracto Technik (Germany) are the world's leading manufacturers of such machines [1]. However, initial hole entry for these

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The detailed research and analysis of modern data on the problem of methods of histological and immunohistochemical researches of connective tissue, bone in particular, was conducted by us so as to evaluate the possibility of creating a single method of bone tissue immunohistochemical analysis.The description was given in detail to most widespread methods of preparation of connective, bone in particular, tissues for the research conduction during experiments connected with the study of bone tissue regeneration including implants with bioactive coverage. The present-day medical data reflects a variety of methods of immunohistochemistry, as well as the experience of their use in complex trauma surgery. However, there is no consensus about which method and material are most reliable when conducting this analysis.