Some new 3-acetyl-2-carboxy-5-methoxy indole (1), 2-carboxy-5-methoxy-3-indolyl chalcones (2-6), 3-(2'-carboxy-5'-methoxyindol-3'-yl)-5-(substituted phenyl)-2-isoxazolines (7-11), 3-(2'carboxy-5'-methoxyindol-3'-yl)-4-(substituted phenyl) aminomethyl-5-(substituted phenyl)-2isoxazolines (12-26) derivatives of indole have been synthesized in the present study. All the prepared compounds have been characterized by elemental and spectral analysis. All the above said compounds have been evaluated for their anti-inflammatory activity and some of them have been found as potential anti-inflammatory agents.

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Traditional cooling systems based on vapor compression are ineffective in humid climates due to their inability to remove moisture below the dew point of the conditioned air, which involves additional effort in the form of an electrical power supply to run vapor compressors. A solid desiccant cooling system reduces powerusage while simultaneously providing fresh and clean air. It is important toexamine and analyze the performance of desiccant dehumidifiers using the Different pattern in the desiccant wheel that will help to develop a more efficient cooling system. Like ahoneycomb, triangular, sinusoidal.To study different type of material used in desiccant wheeel to adsorp the air moisture. Study different simulation technique used in desiccant.