This paper reports on the results obtained the priority recommended strategy for carrying out reconstructive work aimed of the reliability control and safety of Jizzakh main pumping station. It has been established that the safe operation level of Jizzakh main pumping station is supported under the following conditions: The watermark in the pump station forebay are not lower than 314.55 and watermark in the headpond is not higher than 337.80 and not lower than 336.90 for the main units. At the station, no more than 5 “main” and 2 “subsidiary” units work, one “main” unit must be constantly in reserve.