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Long non-coding RNAs (lncRNAs) are endogenous molecules longer than 200 nucleotides, and lack coding potential. LncRNAs that interact with microRNAs (miRNAs) are known as a competing endogenous RNAs (ceRNAs) and have the ability to regulate the expression of target genes. The ceRNAs play an important role in the initiation and progression of various cancers. However, until now, there is no a database including a collection of experimentally verified, human ceRNAs. We developed the LncCeRBase database, which encompasses 432 lncRNA–miRNA–mRNA interactions, including 130 lncRNAs, 214 miRNAs and 245 genes from 300 publications. In addition, we compiled the signaling pathways associated with the included lncRNA–miRNA–mRNA interactions as a tool to explore their functions. LncCeRBase is useful for understanding the regulatory mechanisms of lncRNA.Database URL: http://lnccerbase.it1004.com

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With the trend of digital transformation of enterprises, the use of Internet of Things (IoT) devices is increasing. IoT devices that are not protected by security measures have gradually become targets of attackers. Attackers use weak passwords and software vulnerabilities in the device to invade the device and control it to become a node of the botnet. The Mozi botnet was discovered in December 2019, and its attention has increased day by day, and its influence once exceeded Mirai. After a preliminary reverse analysis of the Mozi samples, we have continued to track the development and changes of the Mozi botnet since February 2021. First, through the in-depth analysis of the communication principles of the Mozi botnet and the distributed sloppy hash table protocol, we have proposed an in-depth analysis of the Mozi botnet. The active detection method of Mozi, through daily and continuous tracking of the number of Mozi nodes, is infinitely close to the boundary of the Mozi network. On the basis of the collected detection data, we give our conclusions on Mozi's node size, global geographic distribution, 24-hour global activity, equipment composition, and Mozi botnet countermeasures.Through this study, we found that the security of IoT devices around the world is not optimistic, and there is an urgent need to increase the security protection