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It has been studied perspective medicinal plant S. sclarea aboveground parts vegetative and generative organs internal features, cultivated on the plot of Iovel Kutateladze Institute of Pharmacochemistry.The aboveground parts of the plant are intensively lined with unicellular or multicellular, conical multicellular (2-11-14) and glandular spherical trichomes; Basal layer cells of curved and curved wall epidermal tissue is characteristic feature for leaf. The ventilation system is represented by diacytic type stomata. The leaf is bifacial, amphistomatic in terms of the location of the ventilation system, while the pulp is characterized by a dorsiventral structure.In the internal structure of aboveground part, the mixed type collenchyma, polygonal structure primary parenchyma and secretory pathways are actively represented. The transport system is monocyclic, differentiation of collateral-type vascular bundles reflected in the stem, leaf stalk, and midrib.

It has been studied perspective medicinal plant Salvia verticillata L. aboveground parts vegetative and generative organs internal features.The aboveground parts of the plant are intensively lined with conical, multicellular (2-7) and glandular spherical trichomes; In the covering tissue of the leaf blade, stalk, and stem the ventilation system is represented by diacytic type stomata. The leaf is bifacial, amphistomatic in terms of the location of the ventilation system, while the pulp is characterized by a dorsiventral structure.In the internal structure of Salvia verticillata aboveground parts coexistence of the plate type collenchyma, polygonal structure primary parenchyma, bast fibre and collenchyma tissue are represented. Collateral-type vascular bundles reflected in the stem, leaf stalk, and midrib; The wood is differentiated into longitudinally arranged, spherically shaped vessels and tracheal elements, vascular tissue one -and two spiral, with porous tracheid wall thickening.

A study of the chemical composition of the essential oil obtained from the aerial parts of Salvia glutinosa L., growing in Georgia, was carried out. The percentage of dominant components was determined by integration, the dominant component in the essential oil are caryophyllene oxide (11.43 %), spathulenol (5.93 %), humulene oxide (4.5 %). From terpene compounds oxygenated sesquiterpenes are dominants. The content of phenolic compounds was determined by using Folin-Ciocalteu reagent in the aqueous, methanol and chloroform fractions of the residual plant material. In aquaeous fraction total phenolic content is 25 ± 2 %, in methanolic fraction 26 ± 3 %, chloroformic -1.8 ± 0.5 %. Fractions antioxidant and anti-inflammatory activity were determined. The methanolic fraction showed antioxidant activity in ORAC test (6 ± 2 micromole TE/mg), aquaeous fraction revealed antioxidant activity (0.61 ± 0.06 micromole TE/mg) using cell culture WS1. Methanolic fraction exhibited high anti-inflammatory activity, 100 % inhibition of NO production, at 52 μg/ml dose, without any significant toxicity

A study of the chemical composition of the essential oil obtained from the aerial parts of Salvia verticillata L., growing in Georgia, was carried out. The percentage of dominant components was determined by internal integration, the dominant component in the essential oil obtained from the leaves is caryophyllene (10.15 %), spathulenol (9.8 %), valeranone (11.9 %), and in the essential oil obtained from the flowers, germacrene D (17.2 %), caryophyllene (9.43 %). The ratio of terpene compounds was determined in the leaves and flowers of Salvia verticillata L., oxygenated sesquiterpenes are 38.43 % and 23.48 % respectively, and sesquiterpene hydrocarbons are 28.03 % and 40.61 %. The content of phenolic compounds was determined using Folin-Ciocalteu reagent in the aqueous, methanol and chloroform fractions of the residual plant material. The methanolic and chloroform fractions showed anti-inflammatory activity, the methanolic fraction -100 % and the chloroform fraction -83 % inhibiting the production of NO from lipopolysaccharide-stimulated mouse macrophage cells (RAW264.7). The aqueous fraction showed antioxidant activity (6.7 ± 0.3 micromole TE/mg) in the ORAC test.