Vibration frequencies of ulnae in 19 children aged between 10 and 15 years old were correlated with their bone mineral densities (BMDs) determined using dual energy x-ray absorptiometry. A correlation analysis method to identify the best frequency range for the vibration analysis was developed. The correlation of subjects' bone vibration frequencies in the identified frequency range with their BMDs were 0.71 (for first order polynomial) and 0.81 (for second order polynomial). This is an initial study, based on a small group of subjects. We are currently continuing the work on a larger number of subjects to confirm the findings.
Sarcoidosis is a multisystem granulomatous disease that can affect any organ in the body, but most commonly the lung. Any part of the thorax may be affected by sarcoidosis, including the lung parenchyma, airways, and mediastinal and hilar lymph nodes. When the parenchyma is involved, sarcoidosis has a predilection for the bronchovascular bundles and subpleural locations. On occasion, the presentation of pulmonary sarcoidosis may be atypical. Atypical presentations may result in a delay in diagnosis as well as unnecessary treatment or diagnostic testing. We discuss four patients with an unusual presentation of thoracic sarcoidosis seen at our Sarcoidosis Clinic.
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