One of the main competencies of the future doctor is developed stress resistance. High level of stress is characteristic of student’s life, but at the same time, it is favourable for opportunities related to the development of viable strategies and attitudes of the individual. It necessitates the study of stress factors of students and ways of its development. Objective. The objective of the article is theoretical and experimental study of psychological factors of stress resistance in medical and dental faculties’ students when forming their professional readiness. The sample included 104 people aged 18 to 20 years, who were 2 to 4 course students of medical and dental faculties of Poltava State Medical University. Methods and materials. The following methods were used in the empirical study: «S. Muddy's stress test», adapted by DA Leontiev and EI Rasskazova, «Test of meaningful life orientations (MLO)» by D. Leontiev and «Boston stress test». The study was conducted in November 2021 remotely, using Google questionnaires. Statistical processing of research results was carried out using Microsoft Excel Office 2010. The statistical significance of difference between groups was determined using the Student's t-test. Results. As a result of the study, some differences in the features of stress resistance between students of dental and medical faculties were revealed. Students of the medical faculty had a higher level of stress resistance. They were more focused on mastering the profession and professional activity and had higher risk-taking rates than dental faculty students. There were also differences in the value-semantic sphere: existential attitudes were more common among medical students and utilitarian attitudes – among dentists. Based on the obtained results, we conducted training on stress resistance in order to increase the level of stress resistance, which should be considered a way to respond to stressful situations.
Antibiotic resistance of pathogens to medications is an essential problem globally. Thus, new medication compositions are one of the ways to solve this problem. This study aimed to investigate the antimicrobial efficacy of the citrate buffer combined with the antibiotic «Amoxiclav» on standard reference strains of microorganisms. We used standard cultures of C. albicans ATCC10231, E. coli ATCC25922, S. aureus ATCC25923, E. faecalis ATCC29213, M. luteus ATCC4698, S. epidermidis ATCC14990 in the study conducted at the Microbiology, Virology and Immunology Department of the Poltava State Medical University. The sensitivity of standard microorganism strains to the composition was studied with a quantitative method of serial dilutions based on CLSI. ISO/TC 212 «Clinical laboratory testing and in vitro diagnostic test systems. 2021». Thus, the results of this study clearly showed a synergistic effect of citrate buffer and amoxiclav on all the reference strains of microorganisms. Reference strains of Staphylococcus aureus and epidermal staphylococcus showed the highest sensitivity to citrate buffer, which was 4 times (p < 0.05) higher than that shown by micrococci, enterococci and fungi, and 8 times (p < 0.01) higher than that of Escherichia coli, which appeared least sensitive to the test substance. Amoxiclav also inhibited the growth of S. aureus ATCC 25923 and S. epidermidis ATCC 14990 and had the minimal effect on the reference strain of E. coli ATCC 25922, the minimal inhibitory concentration of which was 31.3 times (p < 0.0001) higher than that of staphylococci. The proposed citrate buffer-amoxiclav combination significantly increased the antimicrobial efficacy of its components against all the reference strains of microorganisms. Thus, the sensitivity of E. coli ATCC 25922 and M. lysodeikticus ATCC 4698 to the proposed combination increased 8-fold (p < 0.05) compared to their sensitivity to citrate buffer or amoxiclav alone. The sensitivity of Staphylococcus aureus and enterococcі to the composition increased to the maximum: up to 32-fold (p < 0.001) to the buffer and 4‑fold to the antibiotic (p < 0.01). The effect of a significant increase in the sensitivity of C. albicans ATCC10231 strain to the citrate buffer after adding amoxiclav was gone up 128-fold (p < 0.0001). It was the evidence of a synergistic fungicidal action of the antibiotic-citrate buffer combination.
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.
customersupport@researchsolutions.com
10624 S. Eastern Ave., Ste. A-614
Henderson, NV 89052, USA
This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.
Copyright © 2025 scite LLC. All rights reserved.
Made with 💙 for researchers
Part of the Research Solutions Family.