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Synthesis ,characterization of new mono and twin  compounds containing heterocyclic four member ring as, 1,3- diazetine by four steps. The first step; includes  preparation of 2- amino thiazole derivatives [I]a-c via ring closure reaction between acetophenone derivatives   with thiourea in I2,  while the second step includes condensation reaction between 2-amino thaizole derivatives[I]a-c and  p-methoxy benzaldehyde to produce Schiff bases[II]a-c. The third step includes neculophilic attach from imine group toacetyl chloride to give N- acetyl cross bonding[III]a-c.Finally ; the  fourth step is completed by the reaction of N- acetyl derivatives with sodium azide (NaN3) to yield  new 1,3-diazetines. The synthesized compounds were characterized byNMR and IR spectroscopy .The study of liquid crystalline behaviour was carried out using optical polarising microscopy (OPM) and some of them by differential  scanning  calorimetry (DSC) . All compounds were synthesized which showed liquid crystalline properties on heating.

This work involved synthesis and characterization of new mono and twin fused pyrazolone(indazol-3-one) (IV) a-d and thioxo pyrimidine (III) a-d derivatives from Chalcones (mono(I) a,b and twin(I) c,d ) The synthesis of mono chalcones (I) a,b includes the reaction of (p-methoxy or p-methyl) benzaldehyde with 4-amino acetophenone while the twin acetophenone with p-methoxy benzaldehyde to produce twin chalcones (I) c,d , then converted it by Robinson annulations reaction to form the corresponding derivatives (II) a-d afterward reflux the cyclohexenones with hydrazine and some drops of GAA lead to form indazole derivatives (IV) a-d . Pyrimidines were synthesized via the reaction of chalcones with thiourea in NaOH and 80% ethanol. All these compounds are characterized by FT-IR spectroscopy and some of them by 1 HNMR spectroscopy.

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