In Total knee arthroplasty (TKA), not only knee joint affect when we restored limb alignment, but also other joints involved. Ankle joint is one of them. By changing in talar tilt, many studies shown this will lead to increase pain and disturb function of ankle. Patients may end up with unsatisfied result of TKA. Anatomical cut of tibia is use in order to avoid this problem.To compare between pre- and post-operative talar tilt angle (TTA) and ankle clinical assessment by foot function index (FFI) and ankle-hindfoot index (AHI) after anatomical tibial cut (varus 3° with anatomical axis) and conventional tibial cut (perpendicular with anatomical axis) in computer-assisted total knee arthroplastyThis study was retrospective study. We collected data of 70 knees from 54 patients. 32 knees were done by anatomical cut. The rest were conventional cut. We evaluated at pre- and post-operative for TTA. At 12-month follow-up for TTA & ankle clinical assessment.In conventional group, TTA was changed 2.33°(p<0.001) then 0.920(p=0.02) at follow up. In anatomical group, TTA was changed 2°(p=0.037) then 1.38°(p=1.56). Changing of TTA was not significantly different at post-operatively (p=0.76) and follow-up (p=0.98) between 2 groups. FFI& AHI were not significantly different between both groups.