Diabetes Mellitus shortly called as DM is a metabolic disorder which is due to the improper secretion of the insulin by the pancreas. The insensitivity in the reuptake of insulin also causes diabetes. This increases the blood glucose level and affects physiological functions. The majority of the population that is suffering from DM are generally obese or following unhealthy lifestyle habits. There are about half of the world population is suffering from DM and related complications. DM secondary complications include nephropathy, neuropathy, retinopathy and vascular complications like PVD and PAD. Considering the activity of herbs and the safety of the same, an ayurvedic formulation was prepared using herbs, and the same is investigated for the antidiabetic activity. The ayurvedic formulation that is designed in the study is an ayurvedic churnam preparation out of the texts of the Ayurveda books. The polyherbal churnam that is prepared showed a significantly better activity compared to the standard drug and the marketed ayurvedic formulation too. The higher dose of the extract showed higher activity compared to the lower dose of the preparation.

The liver is an important organ in the body that is responsible for the proper metabolism of food and drugs. It eliminates waste material and toxins from food with the help of the enzymes like cytochrome P450. Ficus benghalensis is a very well-known plant that is known for its pharmacological properties like antioxidant, hepatoprotective, immune-boosting, anti-diabetic etc. It also has properties like anti-hypertensive and anti-hyperlipidemic. It was already tested for the hepatoprotective activity, and the extract used was ethanol. Psidium guava is a local plant in tropical countries that are harvested for fruits, and all the plant parts have varied pharmacological activities like anti-diabetic, Anti-inflammatory, anti-hyperlipidemic etc. especially, the leaves of the plant have many significant uses like hepatoprotective which was investigated for the same using methanol extract. The extracts of the Ficus and Guava were incorporated into the syrup formulation, and it was tested for the activity against the hepatotoxicity induced due to the CCl4 and Paracetamol in the albino Wistar rats. The extract and formulation showed a better activity compared to the standard drug.

The procheck synopsis of the model is considered, and the anolea chart is inspected. Presently a little arrangement of an obscure protein is taken, and its grouping arrangement is finished with the assistance of a layout. The swiss model workspace is utilized to at extended last model the structure of the obscure protein. The procheck outline and its anolea are inspected and contrasted and the structure of the known protein. The approval of the structure is assessed.

Thermo Electric Generator is a device which Converts warmth immediately into electric electricity the usage of a phenomenon known as the "Seebeck effect”. Unlike traditional dynamic warmness engines, thermoelectric generators contain no shifting components and are absolutely silent. But for small packages, thermoelectrics can end up competitive due to the fact they are compact, easy (inexpensive) and scalable. Thermoelectric systems may be without problems designed to perform with small heat resources and small temperature difference. The main aim of this project is to use BIO-POTENTIAL as a driving source of power for the implant devices such as Pacemakers. Pacemakers usually use batteries as their power source, and when the battery's period is over, the patient has to undergo surgery to replace the batteries. By using TEG, rapidly undergoing surgery of those pacemakers’s patient can be avoided. The main objective of our project is to power implantable devices using Thermoelectric Generator and avoid further surgeries for the patient.

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