In recent years, sea water has intruded into paddy fields along the coastal areas of the Mekong River Delta. This phenomenon, e.g abiotic stress, has caused rice yields to decrease significantly. A set of six new varieties of rice, including a variety control, IR28, were tested in Long An Province, a region subjected to abiotic stress, from August 2013 to December 2013. The experiments were arranged according to randomized complete block design, with three replications. Results showed that one new mutant cultivar of rice named CTUSM1 was tolerant to soil and water conditions (ECe, EC 6 dSm-1) at the seedling stage; with a yield of 4.43 ton/ha, amylose content of 16.56%, protein content of 6.78%, and a significant resistance to pests and diseases.