The genus Glycyrrhiza (Fabaceae), with over 30 species, includes plants with abundant medicinal properties that have been prevalently used for a long time in traditional medicine. Today, along with the rapid development of modern medicine, this traditional medicine still plays an important role in the research and development of many new drugs. This report emphasized the contribution of some major components of Cam thao (Licorice), one of the species with multifaceted pharmacological effects and used to produce new drugs. Numerous studies have discovered that Licorice contains important substances that affect the physiological activities of living organisms, such as liquirtin, rhamnoliquirilin, liquiritigenin, prenyllicoflavone A, glucoliquiritin apioside, 1metho-xyphaseolin, shinpterocarpine, shinflavanone, licopyranocoumarin, isoflavone, licoarylcoumarin, glycyrrhizin, and manifold components. In this review, the most recent research results within the last 5 years on the pharmacological effects of Licorice are systemized according to the role of Licorice on nervous, respiratory, digestive, immune, reproductive systems (both male and female) and metabolism. It is predicted that Licorice (Fabaceae) will certainly continue to be the subject of manifold scientific works in the future. The effects that have been interesting in the scientific community recently are: oxidation prevention, memory impairment prevention, weight loss, reproductive function improvement in obese men, and immune system function enhancement in many types of cancer. In addition, previous and ongoing studies have shown that Glycyrrhizin, an active ingredient found in Licorice, is effective against Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) because of its antiviral activity. As a result, Licorice can be considered a promising future herbal medicine vital to individual and community health.

Background: Obesity is a global health issue caused by consuming too much energy compared to the body's needs, which negatively impacts almost every organ of the body. As a result, generating an experimental obesity model is critical for researching new drugs to improve obesity and its consequences. Objectives: Generating obesity model of male mice over a 6-week period of feeding by a high-fat diet. Materials and methods: In this experimental research, 24 male mice (Swiss albino) of 3,5 weeks old were divided into 2 groups, each containing 12 mice: control group fed by a normal-fat diet (NFD) and obesity group fed by a high-fat diet (HFD) in a period of 6 weeks. Evaluation was conducted at the beginning of research, every 7 days and at the end of the study. Results: The mean of body weight, weight gain, body length, body mass index (BMI), chest and waist circumference of HFD group had a statistically significant difference from the end of week 2. The morphological difference was more remarkable at week 3 (p<0.001).  After 6 weeks of study, the weight gain rate of HFD group was 131.32% higher than the NFD group. It was also noticeable that the weight of omental fat and renal fat (both sides) in the HFD group was significantly higher than that of the NFD group (p<0,001). Conclusions: Research has successfully generated an obesity model in male mice after a period of 6 weeks by a HFD (640Kcal/100g, 52-53% lipid).