With the growing need for greater operational capacity, information about the effect of application volume and spray nozzles on the quality of pesticide application are essential to obtain greater efficiency in pest management in cotton crops. This study aimed to assess the effect of the spraying volume and nozzles on the deposition of spray solution on cotton crops at the reproductive stage. The treatments of the first experiment correspond to the 55, 67, 140 and 194 L ha-1 volumes obtained by variation of the displacement speed using the XR11004 flat fan nozzle. In the second assay the treatments corresponded to the applications of MGA9004 (hollow cone), XR11004 (flat fan), AIXR11004 (air induction flat fan) and CVIA04 (air induction hollow cone) nozzles with 120 L ha-1. An artificial brilliant blue food dye (FD&C 1) was used as a tracer (2.5 g L-1) to determine the deposited volumes on the leaves of the upper, middle and lower third of cotton plants. The results showed that increase in the application volume contributed to obtain the larger deposits in the upper third of the cotton crop during its reproductive phase, especially up to 140 L ha-1, but did not exhibit a significant increase of the deposition in the middle and lower thirds of the plants. The MGA9004, XR11004 and AIXR11004 nozzles provided the largest deposits in the three plant sectors. The flat fan nozzles resulted in greater uniformity of deposits in the upper and middle thirds of the plants.