Background: Chickenpox or varicella is a viral disease caused by varicella-zoster virus (VZV) with different complications. Due to traditional belief peoples/villagers avoids treatment and follows some traditional remedies and folk medicine. To change this thinking of villager’s health awareness is mandatory. The main aim of the study was control the outbreak and minimizes the future transmission.Methods: An outbreak was investigated in a village of Goalpara district of Assam, India after getting the permission from DHS (District Health Society). Total 42 (Forty two) numbers of patients affected out of 953 (Nine hundred fifty three) numbers of villagers. Blood samples were collected and serum obtained from the samples.Results: The serum samples were tested for VZV IgM ELISA and found 88.09 % patients positive for VZV. Hygiene was observed very poor during our investigation.Conclusions: Health awareness given to the all villagers and patients were treated symptomatically. Immunization, Proper nutrition, Improve living behavior etc can reduce the rate of outbreak.