Background During the swooped coronavirus pandemic in 2020, the non-pharmaceutical interventions (NPIs) not only controlled the pandemic of coronavirus, but also had impacts on other infectious diseases. Dengue has become a disease that calls for key detection with it spreading rapidly worldwide in recent years. This study aims to discuss the impacts of the potential influence factors on dengue during the coronavirus according to the data of dengue pandemic of different countries around the world. Methods We collected the data of 2019 and 2020 dengue cases from 57 countries around the globe. Through correlation analysis and rank sum analysis, we sought to discuss the potential effects of different factors during the outbreak of COVID-19 on dengue. Results The results showed that dengue case subtractions had a significant correlation with the territorial area, the suffered and the deceased number of COVID-19 cases. Further rank sum analysis indicated that there is a significant difference in the number of dengue fever cases between the two years, countries with different continental locations, 2019 and 2020 GDPs per capita, the gaps between two years, territory areas, populations and coronavirus occurrences. Conclusions The results altogether showed that the coronavirus pandemic affected dengue epidemic on a certain degree. Considering the epidemic of dengue is closely related to national economy, geography and demography, our results also further indicated that individual measures should be taken to suppress the development of dengue in different countries depending on their own circumstances, especially during major health events.