In this paper, the application of equivalent simplified calculation model of isolated structure in super high-rise building is studied. In this paper, the characteristics of isolation structures with different height width ratio are analyzed, and the relationship curve between the limit value of height width ratio of isolation structure and the distance of isolation support is established. From the curve, we can estimate the limit height of the isolated structure when the bearing does not produce tensile stress under different seismic intensities. This paper also analyzes the influencing factors of the height width ratio limit, and puts forward the method of increasing the height width ratio limit. In this paper, a vertical stiffness correction model of isolation bearing is proposed. Compared with the shaking table test results and time history analysis, the modified model can truly reflect the mechanical properties of the isolation bearing.