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NAC with PT follow radical surgery was confirmed to prolong disease-free survival, as compared with radical hysterectomy alone. The results of this study suggest that NAC with PT might be a useful adjunct to surgery in the treatment of stage II SCC presenting as a bulky mass.

LNRH is a safe and feasible surgical management for bulky-stage cervical cancer patients (lesion ≥ 6 cm), and after NAC, the urinary and intestinal function of patients in LNRH group showed better recovery compared with functions in the LRH group. The technique is relatively new, and its oncologic efficiency has not yet been fully established. Prospective randomised controlled studies with an increased number of patients and long-term postoperative follow-up should be carried out to investigate the effect of this therapeutic strategy for bulky-stage cervical cancer.

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