Current solid rocket propellant formulations still employ traditional ingredients utilized since the 1960s, such as hydroxyl terminated polybutadiene (HTPB). Recent advances in energetic polymer see many binders capable of providing higher specific impulse and burn rates over HTPB. As shown by calculations, even slight increases in specific impulse can drastically increase the maximum payload of a launch system. Therefore, replacing HTPB with energetic binders could provide heavy space missions the needed extra boost. Energetic binders could also be paired with chlorine-free energetic oxidizers to synergistically provide a specific impulse exceedingly higher than the current formulation while reducing pollution. A comprehensive evaluation of the synthesis, mechanical properties, and performance of various trending and overlooked energetic polymers is described. Several outstanding candidates show promising properties to replace HTPB.

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Benzodiazepines are one of the most prescribed medications as first-line treatment of anxiety, insomnia, and epilepsy around the world. Over the past two decades, advances in the neuropharmacological understanding of gamma aminobutyric acid (GABA)A receptors revealed distinct contributions from each subtype and produced effects. Recent findings have highlighted the importance of α1 containing GABAA receptors in the mechanisms of addiction and tolerance in benzodiazepine treatments. This has shown promise in the development of tranquilizers with minimal side effects such as cognitive impairment, dependence, and tolerance. A valium-like drug without its side effects, as repeatedly demonstrated in animals, is achievable.

At the present, more than 30 low-voltage intelligent distribution rooms have been built in Yunnan Power Grid, covering incoming cabinets, distribution substations, low-voltage switches and environmental monitoring, etc. The intelligent distribution rooms use the Cloud-Edge-Terminal architecture model for intelligent management, monitoring and control of low-voltage distribution rooms but there are generally problems such as low level of heterogeneous data application, insufficient correlation analysis capability, fault location. However, there are problems such as low level of heterogeneous data application, insufficient correlation analysis capability, inaccurate fault location, excessive network load, insufficient sensing capability of sensing terminals and unreasonable configuration. Based on the application model of low-voltage intelligent distribution network of Yunnan power grid, Our paper intends to summarize the experience and methods to support operation and maintenance, fault repair and customer service and study the differentiated low-voltage intelligent distribution Cloud-Edge-Terminal solution to improve the efficiency of intelligent distribution network operation and maintenance.