Wound healing is a coordinated series of interactions between molecules and cells that results in inflammation, re-epithelization, tissue creation, and remodeling to restore the skin barrier. [1] It is one of the most important subgroups in the broader category of "skin and subcutaneous disorders". A wound is a cellular, anatomic and functional integrity disturbance of the living tissue produced by physical, chemical, electrical or microbiological tissue hazards. They are categorized by the fundamental cause of wound formation. [2] The overall vulnerability of skin and subcutaneous illnesses has grown based upon statistics from the Global Burden of Disease (GBD). Over a ten-year period, the population has increased rapidly, with 605,036, 000 in 2015 compared to 492, 883,000 in 2005. [3] Chronic damage is defined by Werdin et al. 2008 and is not carried out in an ordered and prompt manner after 3 months in order to produce anatomical and functional integrity. [4] The wound healing process completes in three phase: the inflammatory phase (establishment of homeostasis and inflammation), the restorative phase, and the regenerative phase. The

There are several medical conditions that directly or indirectly lead to pulmonary destruction or acute lung injury or Acute Respiratory Distress Syndrome e.g. Sepsis, Inhalation of harmful substances, severe pneumonia, Head, chest, or another major injury, Pancreatitis (inflammation of the pancreas), massive blood transfusions and burns. Due to some incidences involved in the etiology of ARDS and limited information about the epidemiology, recognition, management, and less significant results regarding patients with acute respiratory distress syndrome (ARDS), shows intense research on ARDS is needed. From an earlier time, this syndrome has been given many names, including congestive atelectasis, traumatic adult respiratory distress syndrome and shock lung. Recently, the new definition of ARDS has been published, and this definition suggested severity-oriented respiratory treatment by introducing three levels of severity consistent with PaO2/FiO2 and positive end-expiratory pressure. Lung-protective ventilation is still the key to a better outcome in ARDS. ARDS is said to a selection of etiologies, carries high morbidity, mortality (10to 90%), and financial cost. This review is an attempt to compile all aspects of the management of ARDS.