: Exposure of first instar larvae of rice moth, Corcyra cephalonica to the sublethal concentrations i.e. 4, 8 and 12 ppm of methoprene caused dose-dependent alterations in the biochemical constituents of the eggs (laid within 24 h of mating by different crosses involving one or the other or both sexes emerged from treated culture). Such biochemical changes in eggs might lead to impairment of embyonic and post-embryonic growth and development of this pest, and hence, evolution of a new generation of this lepidopterous pest for the eventual establishment on stored cereals and cereal commodities can be considerably restricted.