No abstract

A library of heterocyclic products with a wide variety of organic residues is produced via a four-component reaction of a,bunsaturated aldehydes, primary amines, carbon monoxide, and ethylene using a multi-reactor station with an array of 96 autoclaves employing the same high-pressure reaction conditions for all catalytic reactions. In the presence of Ru 3 (CO) 12 as a precatalyst, mixtures of chiral g-lactams and 2,3-disubstituted pyrroles are obtained. This combinatorial approach also enables us for the first time to set up rules relating to the effects of specific substituents in the substrates on the outcome of the respective catalytic reaction.

The reaction of α,β‐unsaturated aldehydes, carbon monoxide, and but‐3‐en‐1‐amine in the presence of Ru3(CO)12 as a precatalyst yields 1‐substituted 5,6,7,8‐tetrahydroindolizine derivatives for a wide variety of groups R1 at the C‐3 position of the α,β‐unsaturated aldehyde.

No abstract

The title compound, [Fe(C5H5)(C21H24NO2)], which is produced by the oxidation of 1-(4-tert-butylphenyl)-2-ethyl-3-ferrocenylpyrrole, crystallizes as a racemic mixture in the centrosymmetric space group P21/n. The central heterocyclic pyrrole ring system subtends dihedral angles of 13.7 (2)° with respect to the attached cyclopentadienyl ring and of 43.6 (7)° with the major component of the disordered phenyl group bound to the N atom. The 4-tert-butylphenyl group, as well as the non-substituted Cp ring are disordered with s.o.f. values of 0.589 (16) and 0.411 (16), respectively. In the crystal, molecules with the same absolute configuration are linked into infinite chains along the b-axis direction by O—H...O hydrogen bonds between the hydroxy substituent and the carbonyl O atom of the adjacent molecule.