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The evaluation of phytopharmaceutical, antioxidant and antimicrobial activities still a useful and interesting task, especially for unknown and less used medicinal plants in traditional herbal medicine. These plants represent new sources of active compounds. Corchorus olitorius Linn (Tiliaceae) is an important cultivated edible plant in many Arab countries such as Egypt or Sudan, and extreme east of Algeria, it is used for the preparation of a very popular hot soup (called Molokhia). In West Algeria, this plant is reported to be used, for the first time, for medicinal purposes. In the present study, polyphenols potential and in vitro biological activities of cultivated Corchorus olitorius. L leaves and seeds from the Grand Constantinois region (North-east Algeria) are investigated and some preliminary results exhibit an interesting DPPH free radical scavenging potential and antibacterial and antifungal activities for studied plant proportional to richness in secondary metabolites.