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This is a quantitative descriptive study that investigates the kinetics of salivary CPA in order to minimize the risk of CPA exposure after outpatient chemotherapy. Another aim is to document instructions for the prevention of exposure in the homes of the patients receiving outpatient chemotherapy. Materials and Methods Subjects and SettingPrior to the study, approval was obtained from the ethics committee of Ishikawa Nursing University (project registration number 561) and the 2 facilities that carried out the chemotherapy for breast cancer.We enrolled 31patients (age: 54.7 ± 10.5) who had been diagnosed with breast cancer more than one month previously, had received one cycle of chemotherapy (FEC, EC, CAF, AC treatment protocol

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Objective This study was performed to validate the epidemiology, initial treatment, and clinical practice in lung cancer patients in the Hokushin region, Japan. Methods We surveyed retrospective data of newly diagnosed and registered lung cancer patients in 22 principal hospitals in Hokushin region linked with health insurance claims data for registered patients between 2016 and 2017. Results A total of 5503 lung cancer cases were newly diagnosed in Hokushin region during the study period. These patients consisted of 3677 (66.8%) men and 1826 (33.2%) women, with a median age of 72.2 years (range, 27 – 103 years). Diagnoses were small cell lung cancer in 512 (9.4%) cases, squamous cell carcinoma in 1083 (19.7%), and non-squamous non-small cell lung cancer in 3906 (70.9%). The population with stage I disease in Toyama prefecture (41.1%) was lower than in the other three prefectures associated with reduced selection of initial surgery therapy and increased frequencies of stage IV disease (33.2%) and best supportive care (18.6%). Initial chemotherapy for stage IV non-squamous NSCLC consisted of tyrosine kinase inhibitors in 39.3% of cases for EGFR and 4% of cases for ALK-positive non-squamous NSCLC, followed by platinum compounds (25.9%) non-platinum compounds (12.9%), and immune checkpoint inhibitors (10.2%). Carboplatin was the commonly prescribed first-line cytotoxic chemotherapeutic agent in 65.4% of patients under 75 years old and in 96.7% of patients over 75 years old. Conclusion This study revealed real-world data on epidemiological and treatment status in lung cancer in four prefectures in Hokushin region, Japan.