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A novel steroidal saponin, named aculeoside A, embracing a deoxyaldoketose, 6-deoxy-d-glycero-l-threo-4-hexosulose, was isolated from the underground parts of Ruscus aculeatus. The structure was determined by extensive 2D NMR analysis and hydrolysis. Aculeoside A was active as a cyclic AMP phosphodiesterase inhibitor.
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