Curvularin, 8-dehydrocurvularin, and 8-hydroxycurvularin as well as a minor newmetabolite, 8-methoxycurvularin, wereisolated as fungal metabolites having cytotoxic activity toward sea urchin embryogenesis. Curvularin induced barrel-shaped mitotic spindles and 8-dehydrocurvularin caused miniature spindles. They were shownto act on componentsof the mitotic apparatus and to effectively inhibit cell division. Cell cleavage has great physiological significance for cell biologists. Many chemicals
A new naphthoquinone was isolated from the culture broth of a Penicillium species and its structure was de- surface touching the agar mediumhad disappeared, and then the callus started growing and a secondary metabolite was induced. This paper deals with the isolation and structural elucidation of the active compound (la) together with its biological activities toward plant culture cells and its inducing effect as to secondary metabolites.Isolation and structural elucidation of the active compound (la)The culture broth (41) t, /=7.5Hz) and a prominent peak in the MS spectrum at m/z 220 (M+ -C5H10O) strongly suggested that PO-1 possessed a hydroxyhexyl group as a side chain. A hydroxyl was confirmed to be located at 5' by a 3H doublet at 8
Fig. 1 Typical image of magnetic force microscopy showing the stripe domains in the FePt(001) film. Magnetic domain structure of FePt(001) films, which show huge magnetocrystalline anisotropy, was observed by electron holography and Lorentz microscopy. Although these methods have advantages for the microanalysis of magnetic domains, e.g., the high spatial resolution, detection of the magnetic signal is rather difficult when the magnetization vector is parallel to the inci dent electron beam like the case of FePt (001) films. Here we demonstrate that the intensive observations are possible when the specimen is tilted in a microscope so that the magnetic flux perpendicular to the incident beam is generated. The holography ex periment using the cross_ sectioned specimen also provided useful information about the stray magnetic field of the FePt(001) films. (Received December 25, 2003; Accepted January 30, 2004) Keywords: transmission electron microscopy, magnetic recording, magnetic thin films, L1 0 _ type structure, magnetic domain wall, magnetic anisotropy
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In this study, an investigation of the rural community plan based on the People and Nature Coexistence Zones in Kobe City is conducted. The study area is the Oka rural village, which is a suburban rural village, in Kita Ward, Kobe City. This study aims to clarify the situation and characteristics of the succession of a family and agriculture focusing on generation change, as well as the characteristics and relationship between succession and rural management. The results of a questionnaire answered by the officials of a residents' association, representatives of current generation, and the next-generation successors are analyzed, resulting in three findings: (1) The succession from the current generation to the next generation is diversified in comparison with the succession of the family and agriculture from the previous generation to the present generation. (2) Differences in generations and stability regarding the continuance of the family affect the residents' intentions in rural farming and management. (3) The residents are trying to lay the foundation for the maintenance and management of the rural villages without burdening the next generation, with the farming association as the central figure.
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