Kidney is a principal organ required by the body to play a few huge capacities including the upkeep of homeostasis, directing the extracellular conditions, including, detoxification, and release of harmful metabolites and drugs (Ferguson, Vaidya, & Bonventre, 2008). Thusly, the kidney can be considered as a huge objective organ for exogenous toxicants (Kim & Moon, 2012). The main functions of the kidney are formation of urine, maintenance of water, and electrolyte balance as well as production of hormones and enzymes (Kim & Moon, 2012). The kidneys perform some delicate tasks, especially when they have to deal with unwanted substances (Ferguson et al., 2008). The Kidney involves different cell types sifted through into the nephron, which is the basic utilitarian unit of the kidney. Any lifts that impel loss of these cells can actuate hurt on the kidney and lead to renal failure (Barnett & Cummings, 2018). The clarification behind renal failure can be natural or outer. Outer causes incorporate sepsis, cardiovascular disease, heaviness, diabetes, just as failure of the lung and liver. Normal causes incorporate glomerular nephritis, polycystic kidney sickness, renal fibrosis, and stones (Barnett & Cummings, 2018). Oxidative stress is connected with different